Metformin: The Century-Long Journey of a Diabetes Lifeline
Metformin, a medication taken by millions worldwide for type 2 diabetes, has a fascinating history that spans over a century. Originally derived from the French lilac plant, the drug’s potential was recognized early but largely neglected due to limited understanding and competing treatments. Its rediscovery in the mid-20th century marked a turning point, as researchers demonstrated its effectiveness in lowering blood sugar levels without causing dangerous side effects associated with earlier drugs. Regulatory approval came slowly, reflecting both caution and skepticism from medical authorities. Over time, clinical studies confirmed Metformin’s safety, efficacy, and additional benefits, including potential cardiovascular protection and weight management. Today, it stands as a first-line therapy for type 2 diabetes, celebrated for its affordability, accessibility, and long-term impact on public health. Metformin’s journey from obscurity to global medical staple highlights both scientific perseverance and the evolving understanding of chronic disease management.
